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Takes ice baths 3–5 times per week and maintains a consistent evening sleep routine

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The protein levels of p38, p-p38, and HIF-1α were determined by western blotting using SAPK4 (E-3) (1:1000, sc-271292, Santa Cruz Biotechnology, USA), Phospho-p38 MAPK-T180/Y182 pAb (1:2000, AP0526, ABclonal Biotechnology, China), and HIF-1α (28b) (1:1000, sc-13515, Santa Cruz Biotechnology, USA) antibodies, respectively